Deoxycholic acid induces reactive oxygen species accumulation and promotes colorectal cancer cell apoptosis through the CaMKII-Ca2+ pathway

doi:10.4251/wjgo.v17.i8.107453

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World Journal of Gastrointestinal Oncology

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1948-5204

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World J Gastrointest Oncol. Aug 15, 2025; 17(8): 107453
Published online Aug 15, 2025. doi: 10.4251/wjgo.v17.i8.107453

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Figure 5 Effect of deoxycholic acid on apoptosis of SW480 cells after chelation of intracellular calcium ions. The graphs show the flow cytometry results and statistical plots of SW480 cell apoptosis. ^aP < 0.05, ^bP < 0.01. PE: Phycoerythrin; DCA: Deoxycholic acid.

Citation: Chen JY, Wen JY, Lin JL, Li Y, Wu YZ, Lou LQ, Lou YL, Zuo ZG, Li X. Deoxycholic acid induces reactive oxygen species accumulation and promotes colorectal cancer cell apoptosis through the CaMKII-Ca²⁺ pathway. World J Gastrointest Oncol 2025; 17(8): 107453
URL: https://www.wjgnet.com/1948-5204/full/v17/i8/107453.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i8.107453