Deoxycholic acid induces reactive oxygen species accumulation and promotes colorectal cancer cell apoptosis through the CaMKII-Ca2+ pathway

Figure 2 Deoxycholic acid promotes intracellular and mitochondrial reactive oxygen species accumulation in SW480 and DLD-1 cells. A: Flow cytometry results and statistics of intracellular reactive oxygen species (ROS) in SW480 and DLD-1 cells; B: Confocal microscopy results of intra-mitochondrial ROS in SW480 and DLD-1 cells. ^aP < 0.01. FITC: Fluorescein isothiocyanate; DCA: Deoxycholic acid.