GEN1 regulates cell proliferation, migration, apoptosis and ferroptosis in gastric cancer

Figure 1 GEN1 was over-expressed in gastric cancer. A: Gene expression profiling interactive analysis were used to investigate the expression of GEN1 in gastric cancer (GC); B: Real-time quantitative polymerase chain reaction detected GEN1 mRNA levels in GC cells (n = 3); C: Knockdown of GEN1 was successfully done in AGS cells by transfecting with short hairpin (sh) GEN1-1, shGEN1-2, or shGEN1-3 (n = 3). ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. STAD: Stomach adenocarcinomas; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; CON: Control; shCtrl: Negative control with scrambled shRNA; sh: Short hairpin.