LncRNA SNHG5 modulates cell proliferation and migration through the miR-92a-3p/BTG2 axis in gastric cancer by the PI3K/AKT pathway

Figure 6 Long non-coding RNA small nucleolar RNA host gene 5 overexpression was related to miR-92a-3p, B-cell translocation gene 2, and the PI3K/AKT signaling pathway. A: Western blot analysis was performed to determine the expression of B-cell translocation gene 2 (BTG2), PI3K, p-PI3K, AKT, and p-AKT. With the ratio of BTG2/GAPDH, PI3K/GAPDH, p-PI3K/GAPDH, AKT/GAPDH, and p-AKT/GAPDH, the control was defined as 1; B: Quantitative reverse transcription PCR was applied to detect BTG2. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001; NC: Negative control; BTG2: B-cell translocation gene 2; OE-lncRNA SNHG5: Overexpression of long non-coding RNA small nucleolar RNA host gene 5.