Mesenchymal stem cell-derived lncRNAs NKILA contributes to stemness and chemoresistance by fatty acid oxidation in gastric cancer via miR-485-5p/STAT3

Figure 3 Mesenchymal stromal cells induces fatty acid oxidation in gastric cancer cells. The MKN45 and AGS cells were co-cultured with mesenchymal stromal cells. A: The expression of CPT1 and ACS was measured by qPCR in MKN45 and AGS cells; B: The expression of CPT1 and ACS was measured by qPCR in MKN45 and AGS sphere; C: The CPT1 activity was detected in the cells; D: The β-oxidation was analyzed in the cells; E: The relative ATP levels was determined in the cells. ^aP < 0.01; MSC: Mesenchymal stromal cell.