Importance of landscape exploration and progress in molecular therapies and precision medicine for pancreatic ductal adenocarcinoma

doi:10.4251/wjgo.v17.i7.103337

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jul 15, 2025; 17(7): 103337
Published online Jul 15, 2025. doi: 10.4251/wjgo.v17.i7.103337

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Figure 1 Progression model of pancreatic ductal adenocarcinoma in which normal acinar cells (left) transform into precursor lesions (pancreatic intraepithelial neoplasms) (right). The degree of histological progression is associated with an accumulation of specific genetic changes. DM: Ductal metaplasia; PanIN: Pancreatic intraepithelial neoplasms; PDAC: Pancreatic ductal adenocarcinoma; KRAS: Kirsten rat sarcoma oncogene; BRCA2: Breast cancer susceptibility gene 2.

Citation: Hendi M, Zhang B, Mou YP, Cai XJ. Importance of landscape exploration and progress in molecular therapies and precision medicine for pancreatic ductal adenocarcinoma. World J Gastrointest Oncol 2025; 17(7): 103337
URL: https://www.wjgnet.com/1948-5204/full/v17/i7/103337.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i7.103337

Hendi M, Zhang B, Mou YP, Cai XJ. Importance of landscape exploration and progress in molecular therapies and precision medicine for pancreatic ductal adenocarcinoma. World J Gastrointest Oncol 2025; 17(7): 103337 [PMID: 40697241 DOI: 10.4251/wjgo.v17.i7.103337]

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