Molecular surveillance-informed personalized multidisciplinary therapy achieves prolonged survival in a patient with Lynch syndrome-associated colorectal cancer: A case report

Figure 4 Dynamic changes in CREBBP gene expression levels at different time points in patients with specific mutations in exons 25 (F1397 Lfs*62) and 26 (R1446H). Mutation abundance was calculated as the percentage of mutant reads relative to total reads at each position.