RPF2 regulates the protein kinase B/mammalian target of rapamycin pathway in the pathogenesis of Helicobacter pylori

Figure 1 RPF2 and protein kinase B/mammalian target of rapamycin expression in Helicobacter pylori-infected cells. A: Western blots of RPF2 and protein kinase B (AKT)/mammalian target of rapamycin (mTOR); B: RPF2 mRNA level (1.00 ± 0.02 vs 5.10 ± 0.23); C: RPF2 protein levels (1.00 ± 0.05 vs 1.70 ± 0.12); D: Phospho-AKT protein levels; E: Phospho-mTOR protein levels. Mean ± SE. ^aP < 0.05. ^bP < 0.01. ^dP < 0.0001. AKT: Protein kinase B; p-AKT: Phospho-protein kinase B; mTOR: Mammalian target of rapamycin; p-mTOR: Phospho-mammalian target of rapamycin; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; H. pylori: Helicobacter pylori.