Prognostic value of preoperative fibrinogen, neutrophil-to-lymphocyte ratio, serum alpha-fetoprotein, and prealbumin for patients with primary liver cancer undergoing transarterial chemoembolization

Table 6 Predictive value of factors in primary liver cancer patients undergoing transarterial chemoembolization

Parameters	Best_threshold	Sensitivities	Specificities	AUC	Youden_index	F1_score
Hepatitis C (no/yes: 0/1)	0.500	0.243	0.909	0.576	0.152	0.360
Tumor diameter (cm)	9.100	0.324	0.886	0.596	0.210	0.444
Number of tumors (no/yes: 0/1)	0.500	0.365	0.784	0.574	0.149	0.450
Portal vein thrombosis (no/yes: 0/1)	0.500	0.703	0.489	0.596	0.192	0.608
Duration of surgery (minutes)	97.500	0.932	0.352	0.606	0.284	0.091
AFP (ng/mL)	74.000	0.986	1.000	0.986	0.986	0.993
AST (U/L)	45.500	0.581	0.705	0.605	0.286	0.601
PA (mg/L)	168.25	0.662	0.602	0.625	0.264	0.329
FIB (g/L)	3.215	0.473	0.795	0.617	0.268	0.551
NLR	4.495	0.351	0.920	0.610	0.271	0.486
F-NLR (0/1/2)	0.500	0.797	0.443	0.645	0.240	0.648

AUC: Area under the curve; AFP: Alpha-fetoprotein; AST: Aspartate aminotransferase; FIB: Fibrinogen; F-NLR: Fibrinogen and neutrophil-to-lymphocyte ratio; NLR: Neutrophil-lymphocyte ratio; PA: Prealbumin.