Epidemiological trends of cholangiocarcinoma and gallbladder cancer in Northeastern Italy: Administrative analysis over a 17-year period (2007-2023)

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May 15, 2025 (publication date) through Jun 8, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. May 15, 2025; 17(5): 104229
Published online May 15, 2025. doi: 10.4251/wjgo.v17.i5.104229

Table 2 Description of the sample

Characteristic	Total	Intrahepatic CCA	Extrahepatic CCA	Gallbladder cancer and unspecified biliary tract	P value
Gender
Males	5527 (51.3)	1793 (56.6)	1959 (54.7)	1775 (44.1)	< 0.001
Females	5251 (48.7)	1377 (43.4)	1624 (45.3)	2250 (55.9)
Age group (years)
0-44	160 (1.5)	68 (2.1)	44 (1.2)	48 (1.2)	< 0.001
45-54	547 (5.1)	189 (6.0)	165 (4.6)	193 (4.8)
55-64	1615 (15.0)	545 (17.2)	441 (12.3)	629 (15.6)
65-74	3184 (29.5)	1027 (32.4)	1000 (27.9)	1157 (28.7)
75 +	5272 (48.9)	1341 (42.3)	1933 (53.9)	1998 (49.6)
Age	72.9 ± 11.3	71.3 ± 11.5	74.1 ± 11.1	73.2 ± 11.2	< 0.001
Hospital stay (days)	16.9 ± 16.5	15.9 ± 15.5	18.1 ± 18.1	16.6 ± 16.5	< 0.001
Hospitalization regimen
Ordinary	9893 (91.8)	2834 (89.4)	3401 (94.9)	3658 (90.9)	< 0.001
Day surgery	790 (7.3)	326 (10.3)	164 (4.6)	300 (7.5)
Week surgery	95 (0.9)	10 (0.3)	18 (0.5)	67 (1.7)
Biliary tract cancer in main diagnosis	8094 (75.1)	2458 (77.5)	2754 (76.9)	2882 (71.6)	< 0.001
Surgery during hospital stay	9246 (85.8)	2730 (86.1)	3143 (87.7)	3373 (83.8)	< 0.001
In-hospital mortality	1903 (17.7)	574 (18.1)	609 (17.0)	720 (17.9)	NS
Total	10778 (100.0)	3170 (100.0)	3583 (100.0)	4025 (100.0)

Data are presented as mean ± SD or n (%). CCA: Cholangiocarcinoma; NS: Not significant.

Citation: Baldo V, Cozza A, Grego V, Furlan P, Cozzolino C, Saia M, Cocchio S, Floreani A. Epidemiological trends of cholangiocarcinoma and gallbladder cancer in Northeastern Italy: Administrative analysis over a 17-year period (2007-2023). World J Gastrointest Oncol 2025; 17(5): 104229
URL: https://www.wjgnet.com/1948-5204/full/v17/i5/104229.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i5.104229