Long noncoding RNA SNHG5 promotes 5-fluorouracil resistance in colorectal cancer by regulating miR-26b/p-glycoprotein axis

Figure 4 SNHG5 promotes 5-fluorouracil resistance in colorectal cancer in vivo. A: Tumor growth after treatment with 5-fluorouracil was assessed using the following formula: V = 1/2 × a² × b, where a is tumor length and b is tumor width; B: Representative images of trimmed tumors; C: Tumor weight was calculated; D: Ki-67 expression was evaluated in tumor tissues by immunohistochemistry (scale bar = 400 μm). ^aP < 0.05. ^bP < 0.01. Con: Control; shSNHG5: SNHG5-short hairpin RNA; shNC: Negative control-short hairpin RNA; 5-Fu: 5-fluorouracil.