Association of complement components with risk of colorectal cancer: A systematic review and meta-analysis

Table 2 Potential sources of heterogeneity for association between positive expression of complement component proteins and colorectal cancer by region

Subgroup	Study number	Risk ratio (95%CI)	I2	P value
CD55
Asian	2	16.88 (8.49-33.52)	65%	< 0.001
Non-Asian	2	1.49 (0.19-11.97)	88%	0.71
CD59
Asian	2	6.63 (4.06-10.82)	63%	< 0.001
Non-Asian	3	1.97 (1.22-3.18)	0%	0.006
CD46
Asian	2	3.66 (1.75-7.64)	92%	0.040
Non-Asian	2	4.37 (1.95-9.78)	0%	< 0.001

CI: Confidence interval; CD: Cluster of differentiation.