METTL5 promotes cell proliferation, invasion, and migration by up-regulating Toll-like receptor 8 expression in colorectal cancer

Table 1 Associations of METTL5 expression with clinical parameters in colorectal cancer

Variable		METTL5 expression		P value
		Low (n = 75)	High (n = 75)
Gender	Female	31	40	0.141
	Male	44	35
Age (yr)	> 55	48	51	0.605
	≤ 55	27	24
Tumor size (cm)	> 3.5	55	56	0.852
	≤ 3.5	20	19
Vascular invasion	Positive	35	37	0.744
	Negative	40	38
Nerve invasion	Positive	31	36	0.412
	Negative	44	39
Differentiation degree	High/median	25	45	0.001
	Low	50	30
Depth of infiltration	T1/T2	50	49	0.863
	T3/T4	25	26
Positive lymph nodes	≥ 3	10	16	0.196
	< 3	65	59
TNM stage	I/II	57	26	< 0.001
	III/IV	18	49

TNM: Tumor-node-metastasis.