Review
Copyright ©The Author(s) 2024.
World J Gastrointest Oncol. Apr 15, 2024; 16(4): 1134-1153
Published online Apr 15, 2024. doi: 10.4251/wjgo.v16.i4.1134
Figure 2
Figure 2 Intrinsic and extrinsic mechanisms of T cell-associated immunosuppression. MDSCs: Myeloid-derived suppressor cells; TME: Tumor microenvironment; TCR: Intrinsic T-cell receptor; TAM: Tumor-associated macrophage; IRs: Inhibitory receptors; TIM-3: Mucin-3/T-cell immunoglobulin; LAG-3: T-cell activation gene; TGF: Transforming growth factor; PD-1: Programmed cell death-1; IL: Interleukin; TNF-α: Tumor necrosis factor-α; IFN-γ: Interferon-gamma.