Influence of transcatheter arterial embolization on symptom distress and fatigue in liver cancer patients

Table 4 Generalized estimating equation multivariate regression analysis of factors influencing fatigue in patients following transcatheter arterial embolization

Variables	Regression coefficient	SE	Wald χ2	P value
Gender (male vs female)	0.36	1.38	0.07	0.793
Marital status (married vs single)	-3.05	1.46	4.35	0.037
Marital status (married vs single)	-0.93	1.60	0.34	0.558
Family accompaniment (yes vs no)	5.62	1.64	11.69	0.001
Educational level
Junior high school or below vs high school/vocational	0.97	2.02	0.23	0.631
Junior high school or below vs college or above	0.52	2.03	0.07	0.796
Days after embolization
Day 2 vs day 1	-1.01	0.79	1.64	0.200
Day 3 vs day 1	-1.05	0.93	1.28	0.258
PST
1 vs 0	-2.54	1.17	4.70	0.030
2 vs 0	2.69	5.13	0.27	0.601
Continuous variables
Age	-0.20	0.07	7.29	0.007
Tumor size	0.18	0.21	0.79	0.373
Number of TAE procedures	0.16	0.19	0.74	0.390
TAE dose	-0.09	0.17	0.31	0.576
AST on post-TAE day 1	-0.003	0.005	0.46	0.498
ALT on post-TAE day 1	0.003	0.015	0.41	0.523
Total bilirubin on post-TAE day 1	-0.70	1.12	0.39	0.532
Cortisol on post-TAE day 1	0.01	0.07	0.02	0.880
Total symptom distress score	0.53	0.06	79.89	0.001

TAE: Transcatheter arterial embolization; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; PST: Physical functional status.