Mechanism of pachymic acid in the treatment of gastric cancer based on network pharmacology and experimental verification

doi:10.4251/wjgo.v16.i1.30

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Jan 15, 2024 (publication date) through Jun 9, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical and Translational Research

World J Gastrointest Oncol. Jan 15, 2024; 16(1): 30-50
Published online Jan 15, 2024. doi: 10.4251/wjgo.v16.i1.30

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Figure 6 Effect of pachymic acid on the expression of PI3K/AKT pathway and apoptosis-related proteins in gastric cancer cell line HGC-27. A and B: The impact of pachymic acid (PA) on the expression of proteins connected to the PI3K/AKT signaling pathway in HGC-27 cells; C and D: The impact of PA on the expression of apoptosis-related proteins in HGC-27 cells. All experiments were repeated three times and the data were expressed as mean ± SD, ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. NC: Negative control; PA: Pachymic acid.

Citation: Du YH, Zhao JJ, Li X, Huang SC, Ning N, Chen GQ, Yang Y, Nan Y, Yuan L. Mechanism of pachymic acid in the treatment of gastric cancer based on network pharmacology and experimental verification. World J Gastrointest Oncol 2024; 16(1): 30-50
URL: https://www.wjgnet.com/1948-5204/full/v16/i1/30.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i1.30