Mechanism of pachymic acid in the treatment of gastric cancer based on network pharmacology and experimental verification

Figure 5 Effect of pachymic acid on the phenotype of gastric cancer cells. A: The viability of HGC-27 cells treated with pachymic acid (PA) for 24 h, 48 h and 72 h were determined; B: The viability of gastric epithelial GES-1 cells treated with PA for 24 h, 48 h and 72 h were determined; C and D: The quantity of generated cell clones; E and F: Apoptosis rate; G and H: Cell cycle distribution. All experiments were repeated three times and the data were expressed as mean ± SD, ^aP < 0.05, ^bP < 0.01, ^cP < 0.001.