Circ_0003356 suppresses gastric cancer growth through targeting the miR-668-3p/SOCS3 axis

Figure 6 Circ_0003356 overexpression suppresses the malignant behavior of gastric cancer cells via sponging miR-668-3p to target SOCS3. A and B: Protein expression of SOCS3 in AGS and HGC-27 cells detected by western blot; C: Cell viability in AGS and HGC-27 cells detected by CCK-8 assay; D: Proliferation of AGS and HGC-27 cells assessed by EdU assay; E: Apoptosis of AGS and HGC-27 cells assessed by flow cytometry; F: Relative migration of AGS and HGC-27 cells detected by wound healing assay; G: Relative invasion of AGS and HGC-27 cells detected by transwell assay; H: Levels of epithelial-mesenchymal transition-related proteins (E-cadherin and N-cadherin) in AGS and HGC-27 cells determined by western blotting. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001.