Diagnostic accuracy of the multi-target stool DNA test in detecting colorectal cancer: A hospital-based study

Table 2 Evaluation of the expression of different tumor markers between cases and controls, n (%)

Variable	Case group		Control group	P value
	Colorectal cancer	Adenomas	Healthy subjects	CRC patients vs healthy controls	Adenoma patients vs healthy controls
AFP
mean ± SD	5.87 ± 17.59	3.03 ± 1.57	3.32 ± 1.36	0.03	0.43
≤ 7 µg/L	47 (92.20)	22 (95.70)	61 (100.00)
> 7.1 µg/L	4 (7.80)	1 (4.30)	0 (0.00)
CEA
mean ± SD	37.12 ± 149.74	5.21 ± 3.58	2.20 ± 1.58	0.00	0.00
≤ 5 µg/L	34 (66.70)	11 (47.80)	56 (91.80)
> 5.1 µg/L	17 (33.30)	12 (52.20)	5 (8.20)
CA199
mean ± SD	63.05 ± 276.78	13.39 ± 10.19	9.77±8.89	0.01	0.15
≤ 25 µ/mL	41 (80.40)	18 (78.30)	59 (96.70)
> 25.1 µ/mL	10 (19.60)	5 (21.70)	2 (3.30)
Complex value
mean ± SD	806.54 ± 289.28	351.61 ± 369.85	105.11 ± 90.95	0.00	0.00
< 165	5 (9.80)	13 (56.52)	59 (96.72)
≥ 165	46 (90.20)	10 (43.48)	2 (3.28)

AFP: Alpha-feto protein; CEA: Carcinoembryonic antigen; CA199: Carbohydrate antigen 199.