N-myc downstream regulated gene 1 inhibition of tumor progression in Caco2 cells

Figure 6 N-myc downstream regulated gene 1 inhibits the proliferation of Caco2 cells. Cell viability was measured using the cell counting kit-8 assay. The cell cycle was measured using flow cytometry. A: Proliferation curves of Caco2 cells at 24 h, 48 h, 72 h and 96 h after N-myc downstream regulated gene 1 (NDRG1) over-expression; B: Statistical histogram of proliferation activity of Caco2 cells at 24 h, 48 h, 72 h and 96 h after NDRG1 over-expression; C: Proliferation curves of Caco2 cells at 24 h, 48 h, 72 h and 96 h after NDRG1 knockout; D: Statistical histogram of proliferation activity of Caco2 cells at 24 h, 48 h, 72 h and 96 h after NDRG1 knockout; E: Cell cycle diagram of GV358-control group; F: Cell cycle diagram of GV358-NDRG1-over-expression group; G: Statistical histogram of proportions of G1, S, and G2 cells after NDRG1 over-expression; H: Cell cycle diagram of pL-control group; I: Cell cycle diagram of pL-NDRG1-knockout group; J: Statistical histogram of proportions of G1, S, and G2 cells after NDRG1 knockout. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001 vs control. Experiments were repeated three times.