Comprehensive analysis of the potential role and prognostic value of sine oculis homeobox homolog family in colorectal cancer

Table 2 Expression levels of sine oculis homeobox homolog family members in different types of malignant tumors

Organs	SIX1		SIX2		SIX3		SIX4		SIX5		SIX6
	RNA	Protein	RNA	Protein	RNA	Protein	RNA	Protein	RNA	Protein	RNA	Protein
Cerebral cortex	-	-	-	NE	-	NE	-	-	-	-	-	-
Thyroid gland	+	-	+	NE	+	NE	+	+++	+	+++	+	-
Lung	+	+	+	NE	+	NE	+	+	+	+	+	-
Esophagus	-	-	-	NE	-	NE	-	-		-	-	-
Stomach	-	-	+	NE	+	NE	+	-	+	+	+	-
Colon/rectum	+	-	+	NE	+	NE	+	++	+	++	+	-
Liver	+	-	+	NE	+	NE	+	++	+	++	+	-
Pancreas	+	+	+	NE	+	NE	+	+	+	++	+	-
Kidney	+	-	+	NE	+	NE	+	+	+	+	+	-
Urinary bladder	+	-	+	NE	+	NE	+	+	+	+	+	-
Testis	+	-	+	NE	+	NE	+	+	+	+	+	-
Prostate	+	++	+	NE	+	NE	+	++	+	+++	+	-
Ovary	+	-	+	NE	+	NE	+	+	+	+++	+	+
Endometrium	+	+	+	NE	+	NE	+	+	+	++	+	-
Cervix uterine	+	++	+	NE	+	NE	+	++	+	+	+	-
Breast	+	++	+	NE	+	NE	+	+++	+	+++	+	-
Skin	-	-	-	NE	-	NE	-	+++	-	-	-	-
Lymph node	-	-	-	NE	-	NE	-	+	-	-	-	-
Bone marrow	-	-	-	NE	-	NE	-	-	-	-	-

-: Not detected; +: Low levels; ++: Medium levels; +++: High levels; NE: Not examined; SIX: Sine oculis homeobox homolog.