Interleukin-34 promotes the proliferation and epithelial-mesenchymal transition of gastric cancer cells

Figure 3 Interleukin-34 regulates the migration and invasiveness of AGS cells. A and B: Wound-healing assay revealed that downregulation of endogenous interleukin (IL)-34 significantly reduced the migration rate; C and D: Downregulation of endogenous IL-34 reduced the number of invaded cells in the transwell assay; E and F: Wound-healing assay revealed that upregulation of endogenous IL-34 significantly increased the migration rate; G and H: Upregulation of endogenous IL-34 increased the number of invaded cells in the transwell assay. Data derived from three independent experiments performed in triplicate and expressed as mean ± SD, and ^aP < 0.05.