Review
Copyright ©The Author(s) 2021.
World J Gastrointest Oncol. Dec 15, 2021; 13(12): 1939-1955
Published online Dec 15, 2021. doi: 10.4251/wjgo.v13.i12.1939
Table 2 The new systemic, surgical and combined approaches to cholangiocarcinoma
Approaches
Systemic therapy(1) Overcoming chemoresistance; (2) Genetic aberration targeted therapy; (3) Immune checkpoint inhibitors; and (4) Neuroendocrine modulation of cancer growth
Surgical therapy(1) Liver venous deprivation; (2) Minimally invasive surgery; and (3) Liver transplantation
Combined therapyLiver transplantation or surgical resection after radiotherapy and/or neoadjuvant treatment