Intraoperative intraperitoneal chemotherapy increases the incidence of anastomotic leakage after anterior resection of rectal tumors

Table 6 Stratification analysis

Variable	P-value	OR	95%CI	Woolf homogeneity test
Gender				P = 0.805
Male	0.002	5.276	1.637-17.000
Female	0.589	3.767	0.335-42.393
Overall	0.003	4.962	1.733-14.206
Diabetes				P = 0.441
Yes	1.000	1.810	0.108-30.436
No	0.001	5.759	1.823-18.193
Overall	0.002	4.941	1.732-14.093
Incomplete intestinal obstruction				P = 0.305
Yes	0.161	2.471	1.712-3.565
No	0.009	3.915	1.313-11.673
Overall	0.003	4.936	1.714-14.217
Tumor location				P = 0.964
Above peritoneal reflection	0.009	4.932	1.513-16.081
Below peritoneal reflection	0.296	5.234	0.529-51.758
Overall	0.002	4.997	1.748-14.286
NOSE surgery				P = 0.209
Yes	0.143	10.000	2.685-37.239
No	0.003	4.354	1.506-12.585
Overall	0.002	4.855	1.727-13.649
Consolidation suture				P = 0.588
Yes	0.422	2.423	1.805-3.253
No	0.002	4.800	1.656-13.910
Overall	0.002	5.162	1.797-14.829
Defunctioning stoma				P = 0.302
Yes	1.000	1.400	0.085-22.978
No	<0.001	6.319	1.994-20.026
Overall	0.002	5.092	1.793-14.461
Transanal tube				P = 0.468
Yes	0.259	3.136	0.684-14.375
No	0.013	6.931	1.463-32.844
Overall	0.004	4.894	1.682-14.241
Number of stapler firings				P = 0.480
1 and 2	0.011	4.136	1.272-13.446
More than 2	0.045	10.364	1.026-104.656
Overall	0.002	4.942	1.733-14.096

OR: Odds ratio; CI: Confidence interval; NOSE: Natural orifice specimen extraction.