©The Author(s) 2018.
World J Gastrointest Oncol. Oct 15, 2018; 10(10): 351-359
Published online Oct 15, 2018. doi: 10.4251/wjgo.v10.i10.351
Published online Oct 15, 2018. doi: 10.4251/wjgo.v10.i10.351
Table 2 Correlation between vascular endothelial growth factor receptor 1 and class III β-tubulin expression with clinicopathological features
| TUBB3 | VEGFR1 | |||||
| Parameter | Low (n) | High (n) | P | Low (n) | High (n) | P |
| Gender | 0.426 | 0.081 | ||||
| Female | 17 | 19 | 22 | 14 | ||
| Male | 22 | 17 | 31 | 8 | ||
| Age (yr) | 0.31 | 1 | ||||
| ≤ 60 | 32 | 26 | 41 | 17 | ||
| > 60 | 7 | 10 | 12 | 5 | ||
| Pre-CEA | 0.203 | 0.244 | ||||
| ≤ 5 | 20 | 16 | 26 | 10 | ||
| > 5 | 8 | 13 | 12 | 9 | ||
| Pre-Hb | 0.801 | 0.206 | ||||
| ≤ 120 | 13 | 13 | 16 | 10 | ||
| > 120 | 26 | 23 | 37 | 12 | ||
| Distance to verge (cm) | 0.608 | 0.792 | ||||
| ≤ 5 | 25 | 21 | 32 | 14 | ||
| > 5 | 14 | 15 | 21 | 8 | ||
| T stage | 0.883 | 0.744 | ||||
| T1 + T2 | 7 | 6 | 10 | 3 | ||
| T3 + T4 | 32 | 30 | 43 | 19 | ||
| Lymph node metastasis | 0.071 | 0.013 | ||||
| Negative | 15 | 7 | 20 | 2 | ||
| Positive | 24 | 29 | 33 | 20 | ||
| Tumor thrombus | 0.25 | 1 | ||||
| Negative | 37 | 31 | 48 | 20 | ||
| Positive | 2 | 5 | 5 | 2 | ||
| Tumor differentiation | 0.754 | 0.939 | ||||
| Poorly | 11 | 9 | 14 | 6 | ||
| Moderately-well | 28 | 27 | 39 | 16 | ||
| Chemotherapy | 0.156 | 0.051 | ||||
| No | 7 | 2 | 9 | 0 | ||
| Yes | 32 | 34 | 44 | 22 | ||
| VEGFR1 | 0.024 | |||||
| Low | 32 | 21 | ||||
| High | 7 | 15 | ||||
- Citation: Kong XQ, Huang YX, Li JL, Zhang XQ, Peng QQ, Tang LR, Wu JX. Prognostic value of vascular endothelial growth factor receptor 1 and class III β-tubulin in survival for non-metastatic rectal cancer. World J Gastrointest Oncol 2018; 10(10): 351-359
- URL: https://www.wjgnet.com/1948-5204/full/v10/i10/351.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v10.i10.351