Hypermethylation of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia

doi:10.4251/wjgo.v1.i1.41

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Oct 15, 2009 (publication date) through Apr 18, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Oct 15, 2009; 1(1): 41-46
Published online Oct 15, 2009. doi: 10.4251/wjgo.v1.i1.41

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Figure 4 Standardization for DNA microarray analysis. A: Microarray images of control DNAs with methylation rates of 0%, 25%, 50%, 75%, and 100%. M: Methylated sequence probe; U: Unmethylated sequence probe. Three replicates of the experiment were used to create standard curves. B: Standard curves were obtained for LOX: y = -49.256x² + 150.4x - 1.0847, R² = 0.9985; p16: y = 24.965x² + 81.528x - 2.9098, R² = 0.9617; RUNX3: y = 44.245x² + 61.71x - 2.8558, R² = 0.984; and TIG1: y = -20.932x² + 133.9x - 11.113, R² = 0.9852.

Citation: Tamura G. Hypermethylation of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia. World J Gastrointest Oncol 2009; 1(1): 41-46
URL: https://www.wjgnet.com/1948-5204/full/v1/i1/41.htm
DOI: https://dx.doi.org/10.4251/wjgo.v1.i1.41