Review
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Mar 15, 2022; 14(3): 568-586
Published online Mar 15, 2022. doi: 10.4251/wjgo.v14.i3.568
Barrett’s esophagus: Review of natural history and comparative efficacy of endoscopic and surgical therapies
Kevin Kyung Ho Choi, Santosh Sanagapalli
Kevin Kyung Ho Choi, AW Morrow Gastroenterology Liver Centre, Royal Prince Alfred Hospital, Sydney 2050, NSW, Australia
Santosh Sanagapalli, Department of Gastroenterology, St Vincent’s Hospital, Darlinghurst 2010, NSW, Australia
Author contributions: Choi KKH collected and analyzed the data and wrote the manuscript; Sanagapalli S conceived the review and critically revised the manuscript.
Conflict-of-interest statement: There were no conflicts-of-interest in the writing of the article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Santosh Sanagapalli, FRACP, MBBS, Doctor, Department of Gastroenterology, St Vincent’s Hospital, Hospital Road, Darlinghurst 2010, NSW, Australia. santosh.sanagapalli@svha.org.au
Received: May 22, 2021
Peer-review started: May 22, 2021
First decision: October 3, 2021
Revised: November 12, 2021
Accepted: February 15, 2022
Article in press: February 15, 2022
Published online: March 15, 2022
Processing time: 292 Days and 2.7 Hours
Core Tip

Core Tip: Barrett’s esophagus (BE) is an important premalignant condition. The last two decades have seen treatment paradigms increasingly shift towards endoscopic eradication therapy for dysplastic and early neoplastic cases, where it appears safe and effective. We herein provide a comprehensive review of the literature relating to Barrett’s natural history and comparative efficacy of surveillance, endoscopic and surgical therapies for BE by histological stage.