Role of surgical resection for non-colorectal non-neuroendocrine liver metastases

Table 8 Summary of studies with relatively large cohort of patients who underwent hepatectomy for liver metastasis from sarcoma

Ref.	Year	Period	No. of patients	MST (mo)	3-ysr (%)	5-ysr (%)	Factors associated with worse overall survival
Lang et al[48]	2000	1982-1996	26 (including 9 second, 2 third resection)	32 (R0 first resection), 21 (R1,2 resection)	NR	13	NR
DeMatteo et al[26]1	2001	1982-2000	561	391	501	301	Time to liver metastasis from the primary tumor diagnosis ≤ 24 mo
Pawlik et al[49]	2006	1996-2005	53 (35Hx, 18RF + Hx, and 13RF), (including 36 GISTs)	472	652	272	Non-GIST
Marudanayagam et al[50]	2011	1997-2009	361 (including 5 GISTs)	24	48	32	Primaly leiomyosarcoma
Groeschl et al[13]3	2012	1990-2009	98	72	60	32	NR
Zhang et al[51]	2015	2000-2009	27	NR	NR	46	Interval from primary tumor diagnosis ≤ 24 mo, extrahepatic disease, positive margins

¹Including some patients with GIST before 1993, GISTs were considered as leiomyosarcomas;

²Including results of RF and patients with GIST;

³As a part of the report of on-colorectal non-neuroendocrine liver metastases. GIST: Gastrointestinal stromal tumor; MST: Median survival time; ysr: Year survival rate; NR: Not reported; Hx: Hepatectomy; RF: Radiofrequency ablation.