Role of surgical resection for non-colorectal non-neuroendocrine liver metastases

Table 3 Summary of studies each of which included ≥ 40 patients who underwent hepatectomy for liver metastasis from gastric cancer

Ref.	Year	Period	No. of patients	MST (mo)	3-ysr (%)	5-ysr (%)	Factors associated with worse overall survival
Ambiru et al[17]	2001	1975-1999	40	12	NR	18	Synchronous metastasis
Adam et al[10]1	2006	1983-2004	64	15	NR	27	NR
Cheon et al[18]	2008	1995-2005	41	18	32	21	Multiple liver metastases
Takemura et al[19]	2012	1993-2011	64	34	50	37	Serosal invasion of primary gastric cancer, maximum hepatic metastasis diameter > 5 cm
Aizawa et al[20]	2014	1997-2010	53	27	NR	18	Multiple liver metastases
Kinoshita et al[21]	2014	1990-2010	256	31	42	31	Serosal invasion of primary gastric cancer, > 3 liver metastases, maximum hepatic metastasis diameter > 5 cm
Tiberio et al[22]	2015	1997-2011	53	13	14	9	NR2
Oki et al[23]	2015	2000-2010	69	41	51	42	Multiple liver metastases, > 2 positive regional lymph node metastases of primary gastric cancer

¹As a part of the report of on-colorectal non-neuroendocrine liver metastases;

²Only risk factors including palliative patients were reported. MST: Median survival time; ysr: Year survival rate; NR: Not reported.