MicroRNAs and clinical implications in hepatocellular carcinoma

doi:10.4254/wjh.v9.i23.1001

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Aug 18, 2017; 9(23): 1001-1007
Published online Aug 18, 2017. doi: 10.4254/wjh.v9.i23.1001

Table 5 Comparison between microRNAs levels in relation to tumour characteristics, α-feto protein level, Okuda staging, and the etiology of liver cirrhosis

MicroRNA 16			MicroRNA 338			MicroRNA 203			MicroRNA 34			MicroRNA 23a			n	Variable(s)
P-value	Range	Median	P-value	Range	Median	P-value	Range	Median	P-value	Range	Median	P-value	Range	Median	n	Variable(s)
0.3910	2⁴-2¹⁷	2¹²	0.3890	2⁴-2¹⁹	2⁷	0.2571	2²-2¹⁷	2⁴	0.0558	2⁴-2¹⁵	2¹³	0.0008^a	2¹-2¹³	2¹¹	11	Less than 5 cm	Size of focal lesions
0.3910	2¹-2²⁵	2¹⁴	0.3890	2¹-2¹⁵	2⁵	0.2571	2¹-2¹⁹	2⁶	0.0558	2²-2²⁰	2¹⁵	0.0008^a	2³-2¹¹⁸	2¹⁴	46	Equal or more 5 cm	Size of focal lesions
0.3026	2³-2²¹	2¹⁴	0.5352	2¹-2¹⁹	2⁶	0.5040	2²-2¹⁹	2⁶	0.8975	2⁴-2²⁰	2¹⁴	0.0001^a	2¹-2¹⁸	2¹¹	32	Single	No. of focal lesions
0.3026	2¹-2²⁵	2¹⁴	0.5352	2²-2¹⁵	2⁶	0.5040	2¹-2⁹	2⁶	0.8975	2²-2¹¹⁹	2¹⁵	0.0001^a	2¹⁴-2¹⁸	2¹⁵	25	multiple	No. of focal lesions
0.9581	2⁹-2¹⁸	2¹⁴	0.9247	2²-2⁹	2⁶	0.7767	2³-2⁹	2⁶	0.8255	2²-2¹⁹	2¹⁴	0.0795	2¹⁰-2¹⁷	2¹⁵	10	Present	Portal vein thrombosis
0.9581	2¹-2²⁵	2¹⁴	0.9247	2¹-2¹⁹	2⁶	0.7767	2¹-2¹⁹	2⁶	0.8255	2⁴-2²⁰	2¹⁴	0.0795	2¹-2¹⁸	2¹³	47	Absent	Portal vein thrombosis
0.8881	2²-2²⁵	2¹⁴	0.8295	2¹-2¹⁹	2⁶	0.0807	2¹-2¹⁷	2⁷	0.3367	2²-2²⁰	2¹⁵	0.9736	2¹-2¹⁸	2¹⁴	36	Less than 200 ng/mL	AFP level
0.8881	2¹-2²¹	2¹⁴	0.8295	2¹-2¹⁵	2⁶	0.0807	2¹-2¹⁹	2⁵	0.3367	2⁷-2¹⁹	2¹⁴	0.9736	2³-2¹⁷	2¹⁴	21	Equal or more 200 ng/mL	AFP level
0.9347	2⁵-2¹⁷	2¹⁴	0.1145	2⁴-2⁹	2⁷	0.4488	2³-2¹⁷	2⁶	0.4396	2⁴-2¹⁵	2¹⁴	0.0001^a	2⁴-2¹³	2¹¹	7	Stage I	Okuda stage
	2³-2²¹	2¹⁴		2¹-2¹⁹	2⁴		2²-2¹⁹	2⁷		2⁹-2²⁰	2¹⁴		2¹-2¹⁸	2¹¹	23	Stage II
	2¹-2²⁵	2¹⁴		2²-2¹⁵	2⁷		2¹-2⁹	2⁵		2²-2¹⁹	2¹⁴		2¹¹-2¹⁸	2¹⁵	27	Stage III
0.1603	2³-2²⁵	2¹⁴	0.4405	2¹-2¹⁹	2⁶	0.4007	2¹-2¹⁹	2⁷	0.7827	2⁴-2²⁰	2¹⁴	0.5433	2¹-2¹⁸	2¹⁴	42	HCV	Etiology of liver cirrhosis
	2¹-2¹⁵	2¹¹		2¹-2⁹	2⁶		2⁴-2¹⁵	2⁵		2¹⁰-2¹⁷	2¹⁴		2³-2¹⁵	2¹⁴	8	HBV
	2⁵-2¹⁶	2¹⁴		2⁴-2⁹	2⁷		2³-2⁶	2⁴		2²-2¹⁹	2¹⁵		2¹⁰-2¹⁷	2¹⁴	7	None

^aThe first column is variable but is here in this copy the last column. HCV: Hepatitis C virus; HBV: Hepatitis B virus.

Citation: Mohamed AA, Ali-Eldin ZA, Elbedewy TA, El-Serafy M, Ali-Eldin FA, AbdelAziz H. MicroRNAs and clinical implications in hepatocellular carcinoma. World J Hepatol 2017; 9(23): 1001-1007
URL: https://www.wjgnet.com/1948-5182/full/v9/i23/1001.htm
DOI: https://dx.doi.org/10.4254/wjh.v9.i23.1001