Basic Study
Copyright ©The Author(s) 2016.
World J Hepatol. Aug 18, 2016; 8(23): 985-993
Published online Aug 18, 2016. doi: 10.4254/wjh.v8.i23.985
Table 2 Effect of adriamycin combined with metformin on the proliferation of HepG2/adriamycin cells (n = 3, mean ± SD)
Adriamycin (μmol/L)24 h
48 h
72 h
ControlMetforminControlMetforminControlMetformin
01.434 ± 0.031.327 ± 0.04a1.477 ± 0.081.357 ± 0.011.695 ± 0.081.507 ± 0.05a
0.011.280 ± 0.061.160 ± 0.01a1.489 ± 0.031.314 ± 0.03a1.505 ± 0.011.378 ± 0.07a
0.11.194 ± 0.101.111 ± 0.091.418 ± 0.011.213 ± 0.02a1.453 ± 0.021.249 ± 0.04a
10.847 ± 0.020.662 ± 0.02a0.661 ± 0.010.661 ± 0.060.753 ± 0.040.508 ± 0.04a
50.628 ± 0.080.458 ± 0.02a0.358 ± 0.020.208 ± 0.03a0.347 ± 0.030.194 ± 0.03a
100.531 ± 0.000.399 ± 0.01a0.162 ± 0.010.062 ± 0.01a0.122 ± 0.010.049 ± 0.01a
200.284 ± 0.010.162 ± 0.01a0.143 ± 0.010.051 ± 0.00a0.084 ± 0.010.027 ± 0.00a