Obese diet-induced mouse models of nonalcoholic steatohepatitis-tracking disease by liver biopsy

Figure 3 Liver weight and hepatic lipid and collagen content at study end. Liver weight at termination (A), hepatic triglyceride content (B), hepatic total cholesterol content (C), and hepatic hydroxyproline (collagen) content (D) at study end. ^aP < 0.05, ^bP < 0.01, ^dP < 0.001. The results are presented as mean ± SEM. Lean chow (n = 9), DIO-NASH (n = 12), ob/ob chow (n = 8), ob/ob NASH (n = 10). NASH: Nonalcoholic steatohepatitis; BW: Body weight; SEM: Standard error of the mean.