Serum complement C4a and its relation to liver fibrosis in children with chronic hepatitis C

Table 1 Clinical, laboratory and histopathological characteristics of the studied patients n (%)

Parameter	HCV patients (n = 30)
Clinical findings
Jaundice	0 (0.0)
Hepatomegaly	4 (13.3)
Splenomegaly	1 (3.3)
Ascites	0 (0.0)
Liver function tests
Total bilirubin (mg/dL)	1.23 ± 1.051
Direct bilirubin (mg/dL)	0.30 ± 0.26
Albumin (g/L)	43.17 ± 7.5
Alanine transaminase (U/L)	55.57 ± 126.16
Aspartate transaminase (U/L)	72.10 ± 131.97
Gamma glutamyl transpeptidase (U/L)	38.90 ± 21.92
Alkaline phosphatase (U/L)	253.48 ± 97.38
Complete blood count
Hemoglobin (g/L)	113.6 ± 11.2
White blood cells (× 103/ L)	8.77 ± 7.52
Platelets (× 103/L)	383.57 ± 390.87
Fibrosis stage
No (F0)	1 (3.3)
Mild (F1)	12 (40)
Moderate (F2-F3)	17 (56.7)
Activity grade
Minimal	10 (33.3)
Mild	20 (66.7)
Steatosis	8 (26.7)

HCV: Hepatitis C virus; F0/1/2/3: Fibrosis score 0/1/2/3.