Comparative effectiveness of traditional chemoembolization with or without sorafenib for hepatocellular carcinoma

Table 4 Statistical analysis for each covariate in univariate cox regression model predicting overall survival

Characteristic	HR (95%CI)	P value
Age (yr)	0.99 (0.95-1.04)	0.79
Etiology	1.04 (0.66-1.63)	0.86
Alcohol
Hepatitis C
Hepatitis C and alcohol
Non-alcohol/non-hepatitis C
HCC histology	0.73 (0.43-1.25)	0.26
Poorly differentiated
Moderately differentiated
Well differentiated
CTP classification	3.84 (1.74-8.51)	0.001
A
B
BCLC staging for HCC	1.58 (1.02-2.46)	0.04
A
B
C
BCLC staging for HCC (excluding stage C)	1.5 (0.66-3.43)	0.34
A
B
MELD score	1.1 (0.98-1.23)	0.08
AFP (ng/mL)	0.99 (0.82-1.20)	0.98
Tumor size seen on CT with the largest diameter (cm)	1.06 (0.93-1.20)	0.41

HCC: Hepatocellular carcinoma; CTP: Child-Turcotte-Pugh; BCLC: Barcelona Clinic Liver Cancer; MELD: Model of end stage liver disease; AFP: Alpha fetoprotein; CT: Computed tomography.