Surgically induced weight loss by gastric bypass improves non alcoholic fatty liver disease in morbid obese patients

Table 1 Criteria used for histological scoring[21]

Steatosis:

0 : None

1: up to 33%

2: 33%-66%

3: > 66%

Hepatocyte ballooning

0: None

1: Occasional, Zone 3

2: “Obvious” Zone 3

3: Marked, predominantly Zone 3

Mallory bodies

0: No Mallory bodies

1: Fewer than two in 10 to 20 × fields

2: More than two in 10 to 20 × fields

Glycogenated nuclei

0: Absent

1: Occasional

2: Several

Lobular inflammation (inflammatory foci per 20 × with a 20 × ocular)

0: None

1: 1 to 2/20

2: Up to 4/20

3: More than 4/20

Portal inflammation

0: None

1: Mild

2: Moderate

3: Severe

Fibrosis score:

Stage 0: No fibrosis

Stage 1: Zone 3 perisinusoidal/pericellular fibrosis; focally or extensively present

Stage 2: Zone 3 perisinusoidal/pericellular fibrosis with focal or extensive periportal fibrosis

Stage 3: Zone 3 perisinusoidal/pericellular fibrosis and portal fibrosis with a focal or extensive bridging fibrosis

Stage 4: Cirrhosis