Discussion on the effect of Honghua Qinggan Shisanwei Wan on regulating macrophage polarization and alleviating liver injury

Figure 4 Honghua Qinggan Shisanwei Wan affects macrophage infiltration and anti-inflammatory factor expression in carbon tetrachloride-induced liver injury. A: The F4/80 expression of liver tissue in the liver injury; B: The expression of F4/80 in liver injury; C: The C-X3-C motif chemokine receptor 1/transforming growth factor-β/YM-1/interleukin-10 expression of liver tissue in the liver injury (400 ×); D: The expression of YM-1 in liver injury (400 ×); E: The expression of transforming growth factor-β in liver injury (400 ×). The regions indicated by arrows represent the injured areas of liver tissue and the corresponding positive expression regions of the gene. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001, ^dP < 0.0001, NS: Not significant. Con: Control; CCl₄: Carbon tetrachloride; HHQG: Honghua Qinggan Shisanwei Wan; CX3CR1: C-X3-C motif chemokine receptor 1; TNF-α: Tumor necrosis factor-α; IL: Interleukin.