Discussion on the effect of Honghua Qinggan Shisanwei Wan on regulating macrophage polarization and alleviating liver injury

doi:10.4254/wjh.118215

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. Jun 27, 2026; 18(6): 118215
Published online Jun 27, 2026. doi: 10.4254/wjh.118215

Table 2 Changes in the expression of macrophage polarization-related genes in Honghua Qinggan Shisanwei Wan

Gene name	D-5	T-5	log2 fold change	P value
Pparg	162.46	98.41	-0.7190	0.00517415
Stat1	723.84	320.51	-1.1774	6.01E-11
Csf1	355.52	200.93	-0.8192	1.19E-05
Stat2	1410.80	895.83	-0.6543	7.52E-06
Tlr2	238.08	75.68	-1.6471	1.21E-09
Nfekbie	105.56	51.49	-1.0276	0.00017910
Csf3r	219.95	117.95	-0.8960	0.00092885
Tlr4	224.86	63.67	-1.8085	1.99E-10
Irf1	709.64	265.39	-1.4161	1.09E-07
Csf1r	3924.30	1401.87	-1.4844	2.11E-12
Csf2rb	750.01	204.98	-1.8676	9.20E-12
Cd163	1221.77	394.60	-1.6296	4.51E-25
Csf2ra	246.42	104.53	-1.2365	7.50E-09
Csf2rb2	280.50	62.45	-2.1636	1.34E-16
CD86	217.67	107.85	-1.0108	1.42E-05
Arg2	23.43	8.33	-1.4792	0.00882463
Klf4	95.40	53.11	0.8507	0.00486715
Stat5b	1046.13	1806.45	0.7879	1.93E-10
Ppargc1a	167.31	376.35	1.1685	5.96E-06
Nr4A3	6.19	49.79	3.0034	2.18E-07
Cebpb	1472.50	4302.12	1.3658	3.08E-09
Ppargc1b	70.46	133.48	0.9218	0.00012760
Nr4A1	70.71	722.02	3.3517	1.15E-06
Nr4A2	6.50	31.72	2.2805	0.00035749

Full Size Table

Citation: Ma CL, Zhang X, Bao X, Zhao LY, Cao LL, Ma CY, Zhang T, Hong M, Bao YL, Hu RP. Discussion on the effect of Honghua Qinggan Shisanwei Wan on regulating macrophage polarization and alleviating liver injury. World J Hepatol 2026; 18(6): 118215
URL: https://www.wjgnet.com/1948-5182/full/v18/i6/118215.htm
DOI: https://dx.doi.org/10.4254/wjh.118215

Ma CL, Zhang X, Bao X, Zhao LY, Cao LL, Ma CY, Zhang T, Hong M, Bao YL, Hu RP. Discussion on the effect of Honghua Qinggan Shisanwei Wan on regulating macrophage polarization and alleviating liver injury. World J Hepatol 2026; 18(6): 118215 [DOI: 10.4254/wjh.118215]

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