Discussion on the effect of Honghua Qinggan Shisanwei Wan on regulating macrophage polarization and alleviating liver injury

doi:10.4254/wjh.118215

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. Jun 27, 2026; 18(6): 118215
Published online Jun 27, 2026. doi: 10.4254/wjh.118215

Table 1 Primer sequences

Gene	Forward primer	Reverse primer
TNF-α	CCCTCACACTCAGATCATCTTCT	GCTACGACGTGGGCTACAG
IL-6	CCAAGAGGTGAGTGCTTCCC	CTGTTGTTCAGACTCTCTCCCT
IL-1β	GCAACTGTTCCTGAACTCAACT	ATCTTTTGGGGTCCGTCAACT
CCL2	TTAAAAACCTGGATCGGAACCAA	GCATTAGCTTCAGATTTACGGGT
F4/80	TGACTCACCTTGTGGTCCTAA	CTTCCCAGAATCCAGTCTTTCC
TGF-β	CTCCCGTGGCTTCTAGTGC	GCCTTAGTTTGGACAGGATCTG
YM-1	CAGGTCTGGCAATTCTTCTGAA	GTCTTGCTCATGTGTGTAAGTGA
IL-10	GCTCTTACTGACTGGCATGAG	CGCAGCTCTAGGAGCATGTG
CX3CR1	GAGTATGACGATTCTGCTGAGG	CAGACCGAACGTGAAGACGAG
NR4A1	TTGAGTTCGGCAAGCCTACC	GTGTACCCGTCCATGAAGGTG
NR4A2	GTGTTCAGGCGCAGTATGG	TGGCAGTAATTTCAGTGTTGGT
INOS	GTTCTCAGCCCAACAATACAAGA	GTGGACGGGTCGATGTCAC
β-actin	GGCTGTATTCCCCTCCATCG	CCAGTTGGTAACAATGCCATGT

TNF-α: Tumor necrosis factor-α; interleukin; IL: Interleukin; CCL2: C-C motif chemokine ligand 2; TGF: Transforming growth factor; CX3CR1: C-X3-C motif chemokine receptor 1; NR4A: Nuclear receptor subfamily 4 group A; iNOS: Inducible nitric oxide synthase.

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Citation: Ma CL, Zhang X, Bao X, Zhao LY, Cao LL, Ma CY, Zhang T, Hong M, Bao YL, Hu RP. Discussion on the effect of Honghua Qinggan Shisanwei Wan on regulating macrophage polarization and alleviating liver injury. World J Hepatol 2026; 18(6): 118215
URL: https://www.wjgnet.com/1948-5182/full/v18/i6/118215.htm
DOI: https://dx.doi.org/10.4254/wjh.118215

Ma CL, Zhang X, Bao X, Zhao LY, Cao LL, Ma CY, Zhang T, Hong M, Bao YL, Hu RP. Discussion on the effect of Honghua Qinggan Shisanwei Wan on regulating macrophage polarization and alleviating liver injury. World J Hepatol 2026; 18(6): 118215 [DOI: 10.4254/wjh.118215]

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