Sex differences in severity, outcomes, and healthcare utilization in alcohol-associated hepatitis

Table 3 Logistic regression analysis of odds of encounter mortality

Attribute	Odds ratio	95%CI	P value
Age group (≤ 34 as referent)
35-44	1.57	0.686-3.592	0.2855
45-54	3.128	1.410-6.939	0.005b
55-64	2.732	1.163-6.418	0.0211a
≥ 65	4.318	1.124-16.589	0.0331a
MELD-Na score (≤ 15 as referent)
16-20	1.163	0.119-11.311	0.8967
21-22	0.264	0.014-4.908	0.3717
23-26	2.41	0.282-20.596	0.4217
27-31	1.981	0.235-16.722	0.5300
≥ 32	6.925	0.851-56.355	0.0704
Diagnoses
Hepatic encephalopathy	2.308	1.403-3.797	0.0010b
Hepatorenal syndrome	2.224	1.394-3.551	0.0008b
Pneumonia	2.078	1.276-3.382	0.0033b
Sepsis	2.309	1.419-3.757	0.0008b
Procedures
Mechanical ventilation	9.301	5.724-15.114	< 0.0001b

^aP < 0.05.

^bP < 0.01.

Stepwise logistic regression considering the following variables: Sex, age class, body mass index class, Model for End-Stage Liver Disease with serum sodium concentration class, ascites, bacteremia, clostridium difficile, esophageal variceal bleed, hepatic encephalopathy, pneumonia, portal vein thrombosis, spontaneous bacterial peritonitis, SUD/AUD, urinary tract infection, pressors, steroids, renal replacement therapy, hemodialysis, N-acetylcysteine, mechanical ventilation. MELD-Na: Model for End-Stage Liver Disease with serum sodium concentration.