Sex differences in severity, outcomes, and healthcare utilization in alcohol-associated hepatitis

Table 1 Inpatient encounter demographics and clinical characteristics by sex, n (%)

Attribute	Overall (n = 1386)	Male (n = 875)	Female (n = 511)	P value
Age at encounter (years)				0.0031b
Median	46	47	45
Range	24-79	25-79	24-75
Age group at encounter				0.0088b
≤ 34	197 (14.2)	112 (12.8)	85 (16.6)
35-44	423 (30.5)	260 (29.7)	163 (31.9)
45-54	449 (32.4)	277 (31.7)	172 (33.7)
55-64	266 (19.2)	188 (21.5)	78 (15.3)
≥ 65	51 (3.7)	38 (4.3)	13 (2.5)
Ethnicity				0.3009
Hispanic/Latino	38 (2.8)	21 (2.4)	17 (3.3)
Non-Hispanic/Latino	1231 (89.8)	772 (89.5)	459 (90.4)
Unknown	102 (7.4)	70 (8.1)	32 (6.3)
BMI (kg/m2)				0.0127a
Median	27.2	27.6	26.6
Range	15.8-69.7	17.3-69.7	15.8-51.3
BMI (kg/m2)				0.2583
≤ 18.5	50 (3.6)	26 (3)	24 (4.7)
18.6-24.9	450 (32.5)	272 (31.1)	178 (34.8)
25-29.9	409 (29.5)	265 (30.3)	144 (28.2)
30-34.9	254 (18.3)	171 (19.5)	83 (16.2)
35-39.9	133 (9.6)	85 (9.7)	48 (9.4)
≥ 40	90 (6.5)	56 (6.4)	34 (6.7)
CCI				0.9201
Median	4	4	4
Range	0-16	0-16	0-13
CCI group				0.1693
Mild (≤ 2)	161 (11.6)	91 (10.4)	70 (13.7)
Moderate (3-4)	628 (45.3)	405 (46.3)	223 (43.6)
Severe (≥ 5)	597 (43.1)	379 (43.3)	218 (42.7)
Discriminant function score				0.2262
Median	41.2	39.9	42.5
Range	0-470	0-470	2-374
Discriminant function score				0.2739
< 32	503 (36.3)	327 (37.4)	176 (34.4)
≥ 32	883 (63.7)	548 (62.6)	335 (65.6)
MELD-Na score				0.3012
Median	41.2	39.9	42.5
Range	11-40	11-40	11-40
MELD-Na score				0.8612
< 15	89 (6)	54 (6.2)	29 (5.7)
16-20	247 (17.8)	151 (17.3)	96 (18.8)
21-22	126 (9.1)	77 (8.8)	49 (9.6)
23-26	292 (21.1)	184 (21)	108 (21.1)
27-21	299 (21.6)	186 (21.3)	113 (22.1)
≥ 32	339 (24.5)	223 (25.5)	116 (22.7)

^aP < 0.05.

^bP < 0.01.

Continuous variables were assessed for significance using Mann Whitney U test while categorical variables were assessed using a χ² test. BMI: Body mass index; CCI: Charlson Comorbidity Index; MELD-Na: Model for End-Stage Liver Disease with serum sodium concentration.