Correlation between gynecomastia and endocrine regulation in patients with metabolic dysfunction-associated fatty liver disease: A cross-sectional study

Table 5 Performance indicators for sex hormone screening for the development of gynecomastia in patients with metabolic dysfunction-associated fatty liver disease

	Area under the curve	Youden’s index	Cut-off value	P value	95%Cl	Sensitivity	Specificity
E2	0.837	0.552	92.9	< 0.001	0.813-0.861	89.1%	66.1%
ETR	0.804	0.471	6.89	< 0.001	0.777-0.831	81.1%	66%
E2_ETR	0.843	0.545	0.29	< 0.001	0.819-0.866	84.4%	70.1%

ETR: Estrogen to androgen ratio; E2: Estradiol.