Association between insulin and liver function tests, liver disease and cirrhosis in population-based cohorts with long term follow-up

Table 1 Baseline characteristics of the male as well as the female cohorts, n (%)

	Men		Women		P value
	N	Mean (SD)	N	Mean (SD)
Age (years)	857	64.8 (4.1)	1228	47.0 (6.3)	< 0.001
Alcohol (g/day)	848	12.8 (18.3)	1227	8.7 (11.5)	< 0.001
Glucose (mmol/L)	852	4.6 (1.1)	1226	4.1 (0.8)	< 0.001
Insulin (mIU/L)	857	13.3 (9.7)	1228	13.9 (7.1)	< 0.001
Coffee (cups per day)	855	3.9 (2.5)	1227	4.6 (2.8)	< 0.001
Waist circumference (cm)	857	95.3 (9.1)	1227	73.7 (8.5)	< 0.001
Body mass index	856	25.3 (3.2)	1228	24.1 (3.7)	< 0.001
Systolic BP (mmHg)	856	152 (23.3)	1228	134 (21.9)	< 0.001
Diastolic BP (mmHg)	855	84 (11.2)	1228	83 (10.8)	0.063
Triglycerides (mmol/L)	846	1.7 (0.9)	1228	1.2 (0.6)	< 0.001
Cholesterol (mmol/L)	848	6.7 (1.2)	1228	6.8 (1.2)	0.020
Smoking	857		1227		< 0.001
Never smoked		204 (23.8)		650 (53.0)
Quit smoking		366 (42.7)		90(7.3)
Still smoking1		287(33.5)		487(39.7)
Leisure time physical activity	854		1228		0.014
Sedentary		118 (13.8)		219 (17.8),
Moderate/regular1		736 (86.2)		1009 (82.2)
Alcohol (m/f) > 210/140 g per week1	848	110 (13.0)	1227	203 (16.5)	0.029
Elevated liver function test1	855	78 (9.1)	311	17 (5.5)	0.052

¹Indicated the numerical expression is n (%).

P values indicated differences between sexes, Mann-Whitney U test, t-test, or χ² test as appropriate. BP: Blood pressure.