Long-term outcomes of early transjugular intrahepatic portosystemic shunts in patients with acute variceal bleeding and cirrhosis

Table 3 Univariate and multivariate Cox regression analysis for overall survival

Characteristics	Univariate analysis		Multivariate analysis
	HR (95%CI)	P value	HR (95%CI)	P value
Treatment, early TIPS vs standard treatment	0.72 (0.27-1.92)	0.511	-	-
Age (years)	1.05 (1.00-1.11)	0.049	1.04 (0.98-1.10)	0.22
Sex, male vs female	0.85 (0.33-2.20)	0.734	-	-
Comorbidities, yes vs no	4.73 (1.54-14.56)	0.007	3.81 (1.16-12.46)	0.027
Bilirubin	1.30 (0.84-2.01)	0.237	-	-
Creatinine	2.24 (0.72-7.01)	0.165	-	-
Child-Pugh score	1.56 (1.09-2.21)	0.014	1.40 (0.90-2.15)	0.132
MELD score	1.09 (1.01-1.18)	0.026	1.06 (0.98-1.16)	0.168

HR: Hazard ratio; CI: Confidence interval; TIPS: Transjugular intrahepatic portosystemic shunts; MELD: Model for end-stage liver disease.