Advances in the diagnosis and management of clinically significant portal hypertension in cirrhosis: A narrative review

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Jun 27, 2025 (publication date) through Jun 25, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jun 27, 2025; 17(6): 104761
Published online Jun 27, 2025. doi: 10.4254/wjh.v17.i6.104761

Table 1 Classification of portal hypertension

Classification	Etiologies
Prehepatic	Portal vein thrombosis
	Splenic vein thrombosis
	Congenital venous abnormalities
Intrahepatic	Presinusoidal: Hepatoportal sclerosis; schistosomiasis; myeloproliferative diseases; sarcoidosis; early stage of primary biliary cholangitis; primary sclerosing cholangitis; congenital hepatic fibrosis; arsenic toxicity
	Sinusoidal: Cirrhosis; alcohol-associated hepatitis; nodular regenerative hyperplasia
	Postsinusoidal: Veno-occlusive disease
Posthepatic	Budd-Chiari
	Heart failure
	Pulmonary hypertension
	Constrictive pericarditis

Citation: Xie XY, Benmassaoud A. Advances in the diagnosis and management of clinically significant portal hypertension in cirrhosis: A narrative review. World J Hepatol 2025; 17(6): 104761
URL: https://www.wjgnet.com/1948-5182/full/v17/i6/104761.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i6.104761