Effect of rapamycin nanoparticles in an animal model of primary biliary cholangitis

Figure 4 Nanoparticles encapsulating rapamycin treatment decreased the lymphocyte expression in the liver and spleen. A: The percentage of CD4-positive T cells in the liver of the treatment group decreased compared with that in the control group; B: A comparison of the control and treatment groups showed that the percentage of CD8-positive T cells in the liver of the treatment group was decreased; C: The expression of B lymphocytes was decreased in the liver of the treatment group; D: There was no difference in CD4-positive T cells in the spleen between the two groups; E: The percentage of CD8-positive T lymphocytes in the spleen of the treatment group decreased compared with that in the control group; F: The expression of B lymphocytes in the spleen was decreased in the treatment group (^aP < 0.05).