Not all reoperative laparoscopic liver resection procedures are feasible for hepatolithiasis patients with a history of biliary surgery

Table 4 Clinical outcomes of the two subgroups of reoperative left hemihepatectomy

Clinical outcomes	Reoperative open left hemihepatectomy (n = 33)	Reoperative laparoscopic left hemihepatectomy (n = 50)	χ²/t/Z value	P value
Selective hepatic blood flow occlusion	29/33 (87.9)	47/50 (94.0)	0.956	0.3261
Operation duration, mean (SD), minute	244.7 (84.7)	318.9 (88.5)	-3.800	0.0002
Blood loss, median (IQR), mL	235.7 (150.0-400.0)	200.0 (100.0-400.0)	-1.411	0.1583
Blood transfusion	13/33 (39.4)	11/50 (22.0)	2.926	0.0871
Conversion to open surgery	-	8/50 (16.0)	-	-
Postoperative intensive care unit stay	5/33 (15.2)	10/50 (20.0)	0.316	0.5741
Postoperative hospital stay, median (IQR), days	13.0 (8.0-21.0)	8.0 (7.0-12.3)	-3.237	0.0013
Early complications within 90 days	21/33 (63.6)	27/50 (54.0)	0.757	0.3841
Major complications within 90 days	1/33 (3.0)	3/50 (6.0)	N/A4	1.000
Reinterventions within 90 days	1/33 (3.0)	3/50 (6.0)	N/A4	1.000
Readmission within 90 days	6/33 (18.2)	10/50 (20.0)	0.042	0.8371
90-day mortality	0/33 (0.0)	0/50 (0.0)	-	-
Initial stone clearance rate5	25/32 (78.1)	36/48 (75.0)	0.104	0.7481
Re-treatment of residual stones5	4/32 (12.5)	6/48 (12.5)	N/A3	1.000
Final stone clearance rate5	26/32 (81.3)	39/48 (81.3)	0.000	1.0001
Stone recurrence6	8/26(30.8 )	2/39 (5.1)	N/A4	0.011
Late complications5	4/32 (12.5)	3/48 (6.3)	N/A4	0.429
Late major complications5	2/32 (6.3)	1/48 (2.1)	N/A4	0.561
Secondary ICC5	0/32 (0.0)	0/48 (0.0)	-	-
Late death due to complications or ICC5	1/32 (3.1)	0/48 (0.0)	N/A4	0.400

¹χ² test was used.

²Student t-test was used.

³Mann-Whitney U test was used.

⁴No χ² value was reported for Fisher's exact test.

⁵One patients in the reoperative open left hemihepatectomy group and 2 in the reoperative laparoscopic left hemihepatectomy group had no postoperative imaging and were excluded.

⁶Six patients in the reoperative open left hemihepatectomy group and 9 in the reoperative laparoscopic left hemihepatectomy group were further excluded due to residual stone.

Data are presented as number/total number (percentage) of patients unless otherwise indicated. IQR: Interquartile range; ICC: Intrahepatic cholangiocarcinoma; N/A: Not applicable.