Review
Copyright ©The Author(s) 2025.
World J Hepatol. May 27, 2025; 17(5): 104724
Published online May 27, 2025. doi: 10.4254/wjh.v17.i5.104724
Table 1 Diagnosis of hepatorenal syndrome
Key points of diagnosis
Cirrhosis with ascites
Increase in serum creatinine ≥ 0.3 mg/dL (26.5 mol/L) within 48 hours or ≥ 50% from baseline value known or presumed to have occurred within the prior 7 days and/or urinary output ≤ 0.5 mL/kg for ≥ 6 hours
Absence of improvement in serum creatinine and/or urine output within 24 hours following adequate volume resuscitation (when clinically indicated)
Absence of strong evidence for alternative explanation as the primary cause of AKI