Determination of “indeterminate score” measurements in lean nonalcoholic fatty liver disease patients from western Saudi Arabia

Table 1 Metabolic parameters in the groups classified by body mass index

Variable	Lean	Overweight	Obese	P1
	mean ± SD	mean ± SD	mean ± SD
Age in yr	49.95 ± 15.34	51.34 ± 14.33	53.34 ±13.43	0.0122
BMI	23.14 ± 1.95	27.70 ± 1.71	35.38 ± 4.62	0.174
HbA1c, %	6.07 ± 1.41	6.51 ± 1.61	6.46 ± 1.39	0.290
ALT in U/L	37.14 ± 66.48	32.52 ± 32.16	30.73 ± 30.72	0.924
AST in U/L	28.30 ± 23.81	26.44 ± 26.96	25.04 ± 20.91	0.093
GGT in U/L	60.40 ± 81.59	56.61 ± 81.28	57.58 ± 95.50	0.141
ALKP in U/L	89.56 ± 52.69	79.77 ± 43.69	82.73 ± 38.86	0.132
Total bilirubin in mg/dL	0.74 ± 1.43	0.81 ± 1.61	0.63 ± 1.08	0.227
Direct bilirubin in mg/dL	0.35 ± 0.60	0.40 ± 1.06	0.29 ± 0.65	0.679
Total cholesterol in mg/dL	182.07 ± 48.19	172.69 ± 49.50	175.03 ± 47.37	0.222
LDL in mg/dL	118.84 ± 42.12	114.81 ± 42.00	115.38 ± 41.05	0.022
TG in mg/dL	118.69 ± 79.73	135.74 ± 88.66	132.65 ± 88.56	0.140
HDL in mg/dL	52.56 ± 16.27	47.30 ± 16.96	48.49 ± 16.50	< 0.001
FibroScan, kPa	7.43 ± 7.87	7.01 ± 8.39	8.12 ± 9.49	0.174
NFS	-2.74 ± 3.13	-2.11 ± 2.25	-1.14 ± 2.13	0.290

¹Pairwise comparison using Bonferroni correction, with P-value of < 0.05 indicating statistical significance.

²Comparison using Kruskal-Wallis test, with P-value of < 0.05 indicating statistical significance.

ALKP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BMI: Body mass index; GGT: Gamma-glutamyl transferase; HbA1c: Glycated haemoglobin; HDL: High density lipoprotein; LDL: Low density lipoprotein; NFS: Nonalcoholic fatty liver disease fibrosis score.