Tongxie Yaofang enhances the homing efficiency of exogenous bone marrow-derived mesenchymal stem cells to the colonic mucosa and alleviates ulcerative colitis

Figure 2 Tongxie Yaofang promotes the migration of bone marrow-derived mesenchymal stem cells in vitro. A: Effects of different concentrations of Tongxie Yaofang-containing serum on bone marrow-derived mesenchymal stem cell proliferation were assessed using the CCK-8 assay; B: Migration rate of bone marrow-derived mesenchymal stem cells measured by scratch assay; C: Scratch assay observed at 24 hours; D and E: Number of migrated cells determined by Transwell assay. Data are shown as mean ± SD, n = 3 independent biological replicates. ^aP < 0.01 vs control group; ^bP < 0.001 vs control group; ^cP < 0.05 vs Tongxie Yaofang group. CON: Control group; TXYF: Tongxie Yaofang; BMSCs: Bone marrow-derived mesenchymal stem cells.