Mesenchymal stem cell-based therapy for peripheral nerve injuries: A promise or reality?

Figure 2 Endogenous regeneration process of the peripheral nervous system. Following injury, Wallerian degeneration occurs, and Schwann cells proliferate and transdifferentiate while acting alongside macrophages to remove cellular and myelin debris. For regeneration Schwann cells form Büngner’s bands and secrete neurotrophic factors that support axonal growth. Created in BioRender. Amorim, R. (2025) https://BioRender.com/z6uzrjj.